Since most well-characterized antioxidants do not exhibit anti-inflammatory activity, it is unlikely that the anti-inflammatory activity of curcumin is due to its antioxidant activity. Because curcumin also exhibits potent antioxidant activity, whether the anti-inflammatory activity is mediated through its antioxidant mechanism is not clear. Therefore, it is not too surprising that turmeric displays activities against a variety of diseases. Recent scientific evidence has indeed demonstrated that turmeric, and curcumin in particular, exhibits potent anti-inflammatory activities as determined by a wide variety of systems. Turmeric has been traditionally described as an anti-inflammatory agent.
It is now well recognized that most chronic diseases are the result of dis-regulated inflammation. When administered orally, curcumin is metabolized into curcumin glucuronide and curcumin sulfonate. There are also suggestions that the mixture of all three is more potent than either one alone. Although in most systems curcumin was found to be most potent, in some systems bisdemethoxycurcumin was found to exhibit higher activity. Whether all three analogues exhibit equal activity is not clear.
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Note : 100% Guarantee Legal and Free VirusĪs indicated earlier, turmeric contains three different analogues of curcumin (curcumin, demethoxycurcumin and bisdemethoxycurcumin).
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